Upgraded from the first generation of RayKol automated vacuum evaporation system MPE, MPE Plus has been optmized from the original functionality. It combines high-throughput evaporation with vacuum concentration, while accurately controlling the negative pressure during the evaporation with gradient control, avoiding the explosion loss of the targeeted substances and solvent, greatly improving accuracy. With an efficient condensation recovery system, it significantly reduces the exhaust emissions in the laboratory and avoids harmful gases causing physical damage to laboratory personnel.